Zoster, a recrudescence of VZ virus infection.

Zoster, a recrudescence of VZ virus infection.

Pathogenesis Varicella and zoster are different clinical manifestations caused by the same (VZ) virus. Infection of a previously uninfected person produces varicella or in some cases an inapparent infection. Zoster is believed to result from the activation of VZ virus which has been present, but inactive, in the patient's dorsal root ganglion cells and/or his skin cells. Most are 'immune' to a ...

Prevalence of Herpes Simplex Virus type-1, 2 and Varicella Zoster Virus (VZV) in Eye Infection

Abstract Background and Aims: Herpes simplex virus (HSV) is a common cause of corneal disease and is the leading infectious cause of corneal blindness among developed nations. This study is aimed to provide an estimation of the incidence of Herpes Simplex Virustype-1, 2(HSV1, 2) and Varicella Zoster Virus (VZV) in tears and swab from eye infection by polymerase chain reaction (PCR) in eye ...

Animal Models of Varicella Zoster Virus Infection

Primary infection with varicella zoster virus (VZV) results in varicella (chickenpox) followed by the establishment of latency in sensory ganglia. Declining T cell immunity due to aging or immune suppressive treatments can lead to VZV reactivation and the development of herpes zoster (HZ, shingles). HZ is often associated with significant morbidity and occasionally mortality in elderly and immu...

Varicella Zoster Virus Infection in Pregnancy

Varicella Zoster Virus Infection in Pregnancy

Varicella and herpes zoster during pregnancy has been associated with birth defects, neonatal varicella, herpes zoster in newborns and infants. The aim of the present study was to determine the consequences for the neonates, whose mothers were closely exposed to varicella zoster virus (VZV) during pregnancy. Fifty six pregnant women with uncertain histories of prior VZV infection, after a close...